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Naltrexone Tablets (nodict By Sun Pharma)

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Brand Name(s) :

Naltrexone Tablets (Nodict by Sun Pharma)

Usage :   Stop Drinking
Active Ingredient : Naltrexone Hydrochloride 50mg
Supplied Form : Tablet
Packaging : Strip of 10 tablets
Qty Price Price per
Tablet
Saving  
50mg x 30 pcs USD 129.00 USD 4.30 -
50mg x 50 pcs USD 199.00 USD 3.98 USD 16.00
50mg x 100 pcs USD 349.00 USD 3.49 USD 81.00
50mg x 150 pcs USD 479.00 USD 3.19 USD 166.50
50mg x 200 pcs USD 599.00 USD 3.00 USD 260.00

Generic Revia (Nodict by Sun Pharma) - Product Information

Generic Revia (Naltrexone tablets) is used for the treatment of alcohol dependence and for stopping the effects of exogenously administered opioids. The main use of Naltrexone (Nodict tablets) is for the treatment of alcohol dependence, since Naltrexone has been shown to decrease heavy drinking. This also holds good in patients who continue drinking while taking Naltrexone tablets, but then it is less effective in helping such people to stop completely.

Generic Revia (Nodict tablets) has not been seen to provide any therapeutic benefit except as part of an suitable plan of management for alcohol and opioid addictions. Nodict tablets are manufactured by Sun Pharmaceutical Industries Ltd. in the strengths of 50 mg.

Name of the Drug

We supply original Nodict tablets manufactured by Sun Pharmaceutical Industries Ltd..

Manufacturer of Nodict Tablets

Sun Pharmaceutical Industries Ltd.  
Website:www.sunpharma.com

Active Ingredient present in Nodict Tablets

The active ingredient present in Nodict tablets is Naltrexone Hydrochloride. Each film-coated tablet of contains 50 mg of Naltrexone Hydrochloride.

Generic Revia (Nodict Tablets) - Dosage

Inorder to decrease the risk of precipitated withdrawal in patients dependent on opioids, or increase of a preexisting subclinical withdrawal syndrome, opioid-dependent patients, including those being treated for alcohol dependence, should be opioid-free (including tramadol) for an interval of a minimum of 7 to 10 days before starting Generic Revia treatment.

Treatment of Alcoholism :
The recommended dosage of Nodict tablets is 50 mg once daily for most patients. Studies that demonstrated the efficacy of Generic Revia as an adjunctive treatment of alcoholism used a dose regimen of Generic Revia 50 mg once daily for up to 12 weeks. Generic Revia tablets should be considered as only one of many factors that will determine the success of treatment of alcoholism. Appropriate compliance-enhancing techniques should be implemented for all parts of the treatment program, especially medication compliance inorder to achieve the best possible results.

Treatment of Opioid Dependence :
Treatment of Opioid dependence should be started with an initial dose of 25 mg of Generic Revia. If no withdrawal symptoms occur, the patient may be started on 50 mg a day thereafter.

Generic Revia (Nodict Tablets) Contraindications

Generic Revia (Nodict Tablets) is contraindicated in the following cases:

  • Patients receiving opioid analgesics.
  • Patients which are currently dependent on opioids, including those currently maintained on opiate agonists (e.g., methadone) or partial agonists (e.g., buprenorphine).
  • Patients in acute opioid withdrawal
  • Any patient who has failed the Naloxone challenge test or who has a positive urine screen for opioids.
  • Any individual with a history of hypersensitivity to Naltrexone Hydrochloride or any other components of Nodict tablets. It is not known if there is any cross-sensitivity with naloxone or the phenanthrene containing opioids

 

Naltrexone Side Effects

The most common side effects of Naltrexone tablets (Nodict) are non-specific gastrointestinal complaints such as diarrhea and abdominal cramping.
The following side effects were reported in 2% or more of the patients during a study conducted on patients being treated with Naltrexone tablets for Alcoholism : nausea (10%), headache (7%), dizziness (4%), nervousness (4%), fatigue (4%), insomnia (3%), vomiting (3%), anxiety (2%) and somnolence (2%).

In case of patients undergoing treatment for Opioid Addiction the following side effects have been reported at an incidence rate of more than 10%: Difficulty sleeping, anxiety, nervousness, abdominal pain/cramps, nausea and/or vomiting, low energy, joint and muscle pain, and headache. The other side effects occuring in less than 10% of patients were Loss of appetite, diarrhea, constipation, increased thirst, increased energy, feeling down, irritability, dizziness, skin rash, delayed ejaculation, decreased potency, and chills.

Warnings and Precautions

The following are the warnings and precutions to be taken when undergoing treatment with Generic Revia (Nodict Tablets):

  • Naltrexone tablets have the ability to cause hepatocellular injury when given in excessive doses.
  • Naltrexone tablets are contraindicated in acute hepatitis or liver failure, and its use in patients with active liver disease must be carefully considered in light of its hepatotoxic effects.
  • Since Naltrexone is a potent antagonist with a prolonged pharmacologic effect (24 to 72 hours), the blockade produced by Naltrexone can be overcome. This is useful in the case of patients who may require analgesia, but poses a potential threat to individuals who attempt, on their own, to overcome the blockade by administering large amounts of exogenous opioids.
  • For emergency situations which may arise in patients receiving fully blocking doses of naltrexone, a suggested plan of management is regional analgesia, conscious sedation with a benzodiazepine, use of non-opioid analgesics or general anesthesia.
  • Severe opioid withdrawal syndromes caused by the accidental ingestion of Naltrexone tablets have been reported in opioid-dependent individuals.
  • Naltrexone and its primary metabolite are excreted mainly in the urine, and caution is recommended in administering the drug to patients with renal impairment.
  • Precautions should be taken when Naltrexone HCl tablets are administered to patients with liver disease.
  • The possibility of suicide is known to be increased in patients with substance abuse with or without concomitant depression. This risk is not decreased by treatment with Naltrexone.

 

Nodict Tablets - Storage and Handling

Nodict tablets should be stored at temperatures below 25° C. Keep out of reach of children and pets.

Naltrexone During Pregnancy

Naltrexone tablets have been classified by the US FDA as pregnancy Category C. Naltrexone has been observed to increase the incidence of early fetal loss when given to rats at doses greater than or equal to 30 mg/kg/day which is 5 times the recommended therapeutic dose, based on body surface area. There are no adequate and well controlled studies conducted in pregnant women. Generic Revia tablets should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Naltrexone Tablets During Nursing

In animal studies, Naltrexone was excreted in the milk of lactating rats that were dosed orally with Naltrexone. It is not known whether Naltrexone is excreted in human milk, Due to the well known fact that many medicines are excreted in human milk, caution should be taken when Generic Revia tablets are administered to a nursing woman.

Buy Generic Revia Tablets (Nodict Pills) Online at Only $3 per Pill

You can buy Generic Revia tablets online from Clear Sky Pharmacy. Nodict 50 mg pills, manufactured by Sun Pharmaceutical Industries Ltd., India are supplied in a blister strip of 10 tablets. The 50 mg tablets cost only $3 per unit when you place an order for 200 tablets.

Disclaimer

The above information is provided to the best of our knowledge and in good faith, it is without a warrant of any kind, expressed or implied.

 

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