Generic Zofran (ondem By Alkem)

Ondem Tablets by Alkem (Generic Zofran) - Product Information

Ondem Tablets are used to help stop the nausea (sick feeling) and vomiting, which can take place after certain treatments such as chemotherapy and radiotherapy. They are also used for the prevention and treatment of nausea and vomiting, which can occur after a surgery. Ondem tablets are manufactured by Alkem Laboratories in the strengths of 4 mg and 8 mg.
We also have in stock Generic Nexium (Nexpro Tablets) which are used to treat symptoms of gastroesophageal reflux disease (GERD) .

Manufacturer of Ondem Tablets

Alkem Laboratories Ltd  
Website: www.alkemlabs.com

Active Ingredient present in Ondem Tablets

The active ingredient present in Ondem tablets (Generic Zofran) is Ondansetron Hydrochloride as the dihydrate. Ondem tablets contain the following inactive ingredients: lactose, magnesium stearate, methyl hydroxypropyl cellulose, microcrystalline cellulose, a small amount of a colouring agent called Opaspray or Opadry yellow, and pregelatinized starch. Each tablet of Ondem contains either 4 mg or 8 mg of the active ingredient Ondansetron Hydrochloride.

Ondem Tablets - Dosage

Do not take more doses, or take them more frequently than your doctor prescribes. If, however, you vomit within one hour of taking the medicine, you should take the same amount of medicine again. Please take the exact quantity of medicine prescribed for you. Swallow each tablet with a drink of water. Do not use the medication in larger amounts, or use it for longer or shorter than recommended by your doctor.
The recommended dosage of Ondem Tablets (Generic Zofran) to treat various indications is given below:
Emetogenic Chemotherapy and Radiotherapy:
The recommended oral dose of Generic Zofran is 8 mg one to two hours before treatment, followed by 8 mg orally 12 hours later. The recommended oral dose is 8 mg to be taken twice daily. To protect against delayed or prolonged emesis after the first 24 hours, oral treatment with Ondansetron should be continued for up to 5 days after a course of treatment.
Post-Operative Nausea and Vomiting:
The recommended oral dose for the prevention of post-operative nausea and vomiting is 16 mg given one hour prior to anaesthesia.

Ondem Tablets (Generic Zofran) - Missed Dose

In case you miss a dose of Generic Zofran and do not feel sick, take the next dose when it is due. If you forget to take your medicine and feel sick or vomit, please take a dose of Ondem tablets immediately. Do not take extra medicine to make up the missed dose.

Ondem Tablets (Generic Zofran) - Interactions

As with most other medications, interactions with other drugs are possible. Inorder to prevent potentially life-threatening reactions tell your doctor about all the medications you take, including those prescribed by other doctors and that vitamins, minerals, natural supplements, alternative medicines and over the counter medications. It is important that your doctor knows about all your medication so that you get the best possible treatment. Please inform your doctor if you are taking carbamazepine, phenytoin, or rifampicin.

If you are taking any medicines containing tramadol, Ondem tablets (Generic Zofran) may decrease its effectiveness. Also, make sure you tell your doctor or your healthcare provider if you are taking:

• Medicines used to treat heart rhythm disorders
• Other drugs that may disturb heart rhythm
• Antipsychotics
• Antidepressants
• Antibiotics or antifungals
• Opiod analgesics (painkillers)
• Other drugs to treat nausea and vomiting
• Asthma drugs
• Cancer drugs
• Diuretics

Also inform your doctor about other medications that affect serotonin including the following

• SSRI (Selective Serotonin-Reuptake Inhibitors) - used to treat depression or anxiety, e.g. escitalopram, citalopram, fluoxetine, paroxetine, sertraline.
• SNRI (Serotonin Noradrenalin Reuptake Inhibitors) - used to treat depression or anxiety, e.g. duloxetine, venlafaxine, desvenlafaxine.
• MAOIs (including the antibiotic linezolid and methylene blue) (Monoamine Oxidase Inhibitors) - used to treat depression, Parkinson's disease, e.g., phenelzine, rasagiline, selegiline.
• drugs that contain tryptophan, or St. John's Wort.

Side Effects of Ondem Tablets

The most common side effects of Ondem tablets (Generic Zofran) in adults are diarrhea, headaches, a sensation of warmth or flushing, constipation, and fever. Although uncommon, low blood pressure and hiccups have also been reported. These are all mild side effects, and while there is no need to stop taking your medicine, you should tell your doctor about these symptoms at your next visit.

Uncommon Side Effects

• Heart problems such as fast/slow heart beat, chest pain
• Seizures
• Upward rolling of the eyes, abnormal muscular stiffness/body movements/shaking

Rare Side Effects

• Eye problems such as blurred vision
• Immediate allergic reaction and symptoms such as swelling of the mouth, throat, difficulty in breathing, rash, hives, increased heart rate
• Disturbance in heart rhythm (dizziness, palpitations, fainting)

Serotonin Syndrome: Symptoms of Serotonin Syndrome have been observed in patients that were taking Ondem Tablets (Generic ZOFRAN®) with certain other medications. The symptoms include:

• agitation, confusion, restlessness, hallucinations, mood changes, unconsciousness, coma.
• fast heartbeat, changes in blood pressure
• Muscle shakes, jerks, twitches or stiffness, overactive reflexes, loss of coordination
• nausea, vomiting, diarrhea, fever, sweating, shivering.

Very Rare Side Effects

• Eye problems such as temporary blindness
• Signs of serious skin reactions (skin rash, redness of the skin, blistering of the lips, eyes or mouth, and skin peeling. )

Ondem Tablets During Pregnancy

Ondem (Ondansetron Hydrochloride) is classified as Pregnancy Category B. Reproduction studies performed in animals at daily oral doses up to 15 and 30 mg/kg/day, respectively, and have shown no evidence of impaired fertility or harm to the fetus due to Ondansetron. There are, however, no adequate and well-controlled studies done in pregnant women. Since reproduction studies done on pregnant animals are not always predictive of human response, Ondem (Generic Zofran) should be used during pregnancy only if clearly needed. Please inform your doctor if you are pregnant or plan to become pregnant during treatment.

Ondem Tablets (Generic Zofran) Use by Nursing Mothers

Ondem (Ondansetron Hydrochloride) is excreted in the breast milk of rats. It is presently not known if Ondansetron is excreted in human milk. Since many medicines are excreted in human milk, caution should be exercised when ondansetron is administered to a nursing woman. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Ondem Tablets (Generic Zofran) - Warnings & Precautions

You should not use this medicine if you are allergic to ondansetron or any inactive ingredient present in Ondem (Generic Zofran), to similar medicines such as dolasetron (Anzemet), granisetron (Kytril), or palonosetron (Aloxi). Do not take this medicine if you are also using apomorphine (Apokyn).
Patients should be made aware of the possibility of serotonin syndrome with simultaneous use of Ondem (Generic Zofran) and another serotonergic agent such as medications to treat depression and migraines.
Profound hypotension and loss of consciousness has been reported when apomorphine was administered with Ondem (Ondansetron). Hence concomitant use of apomorphine with Ondansetron is contraindicated.
To make sure you can safely take Zofran, please inform your doctor if you have any of these other conditions:

• Liver disease
• Heart disease, congestive heart failure, a heart rhythm disorder;
• An electrolyte imbalance (such as low levels of potassium or magnesium in your blood); or
• A personal or family history of Long QT syndrome.
• Ondem orally disintegrating tablets may contain phenylalanine. Please inform your doctor if you have phenylketonuria (PKU).

Ondansetron should not be given to a child younger than 4 years old.

Buy Ondem 4 mg and 8 mg Tablets Online at Only $0.27 per Pill

You can buy Ondem 4 mg and 8 mg tablets (Generic Zofran) online from Clear Sky Pharmacy. Ondem pills, manufactured by Alkem Laboratories Ltd, India are supplied in a strip of 10 tablets. The 4 mg tablets cost only $0.27 per unit when you place an order for 300 tablets.

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