Generic Hydrocortisone Tablets

Generic Hydrocortisone Tablets (Hisone 5 mg, 10 mg & 20 mg) - Product Information

Generic Hydrocortisone Tablets (Hisone) is commonly used for various inflammatory, autoimmune, hormonal, and other conditions where a corticosteroid may be used, which include the following conditions like Severe allergic conditions, Certain disorders of your skin, hormonal system, digestive tract, blood, nervous system, eyes, kidneys, or lungs, Certain types of cancer (to ease the symptoms), Rheumatic diseases (such as rheumatoid arthritis), which are painful and inflammatory conditions that affect your joints, tendons, ligaments, bones, and muscles and Reduced adrenal gland function (adrenal insufficiency). This medicine is also used for replacement therapy in congenital adrenal hyperplasia in children.

Hisone tablets are manufactured by Samarth Life Sciences Private Limited, India, in the strengths of 5 mg, 10 mg and 20 mg. We also have in stock Generic Prednisone (Omnacortil Tablets) which is used as an anti-inflammatory or immunosuppressive agent to treat certain allergic, dermatologic, gastrointestinal, hematologic, ophthalmologic, nervous system, renal, respiratory, rheumatologic, specific infectious diseases or conditions and organ transplantation.

Name of the Drug

We supply original Hisone tablets manufactured by Samarth Life Sciences Private Limited, India.

Manufacturer of Hisone Tablets

Samarth Life Sciences Private Limited, India.  
Website: https://samarthlife.com/

Active Ingredient present in Hisone Tablets

The active ingredient present in Hisone tablets Hydrocortisone. Each Hisone tablet contains 5 mg, 10 mg or 20 mg of Hydrocortisone.

Uses of Hisone Tablets

Hisone Tablets (Generic Hydrocortisone Tablets) provides relief for inflamed areas of the body. This medicine is used to treat a number of different conditions, such as inflammation (swelling), severe allergies, adrenal problems, arthritis, blood or bone marrow problems, eye or vision problems, lung or breathing problems (eg, asthma), lupus, skin conditions, and ulcerative colitis.
Hydrocortisone is a corticosteroid (cortisone-like medicine or steroid). It works on the immune system to help relieve swelling, redness, itching, and allergic reactions.
Hisone Tablets are indicated in the following conditions. 1. Endocrine Disorders:
Primary or secondary adrenocortical insufficiency (hydrocortisone or cortisone is the first choice; synthetic analogs may be used in conjunction with mineralocorticoids where applicable; in infancy mineralocorticoid supplementation is of particular importance)
Congenital adrenal hyperplasia
Non suppurative thyroiditis
Hypercalcemia associated with cancer
2. Rheumatic Disorders :
As adjunctive therapy for short-term administration (to tide the patient over an acute episode or exacerbation) in:
Psoriatic arthritis
Rheumatoid arthritis, including juvenile rheumatoid arthritis (selected cases may require low-dose maintenance therapy)
Ankylosing spondylitis
Acute and subacute bursitis
Acute nonspecific tenosynovitis
Acute gouty arthritis
Post-traumatic osteoarthritis
Synovitis of osteoarthritis
Epicondylitis
3. Collagen Diseases :
During an exacerbation or as maintenance therapy in selected cases of: Systemic lupus erythematosus Systemic dermatomyositis (polymyositis) Acute rheumatic carditis
4. Dermatologic Diseases :
Pemphigus Bullous dermatitis herpetiformis Severe erythema multiforme (Stevens-Johnson syndrome) Exfoliative dermatitis Mycosis fungoides Severe psoriasis Severe seborrheic dermatitis
5. Allergic States :
Control of severe or incapacitating allergic conditions intractable to adequate trials of conventional treatment:
Seasonal or perennial allergic rhinitis
Serum sickness
Bronchial asthma
Contact dermatitis
Atopic dermatitis
Drug hypersensitivity reactions
6. Ophthalmic Diseases :
Severe acute and chronic allergic and inflammatory processes involving the eye and its adnexa such as:
Allergic conjunctivitis
Keratitis
Allergic corneal marginal ulcers
Herpes zoster ophthalmicus
Iritis and iridocyclitis
Chorioretinitis
Anterior segment inflammation
Diffuse posterior uveitis and choroiditis
Optic neuritis
Sympathetic ophthalmia
7. Respiratory Diseases :
Symptomatic sarcoidosis
Loeffler’s syndrome not manageable by other means
Berylliosis
Fulminating or disseminated pulmonary tuberculosis when used concurrently with appropriate antituberculous chemotherapy
Aspiration pneumonitis
8. Hematologic Disorders :
Idiopathic thrombocytopenic purpura in adults
Secondary thrombocytopenia in adults
Acquired (autoimmune) hemolytic anemia
Erythroblastopenia (RBC anemia)
Congenital (erythroid) hypoplastic anemia
9. Neoplastic Diseases :
For palliative management of:
Leukemias and lymphomas in adults
Acute leukemia of childhood
10. Edematous States :
To induce a diuresis or remission of proteinuria in the nephrotic syndrome, without uremia, of the idiopathic type or that due to lupus erythematosus.
11. Gastrointestinal Diseases :
To tide the patient over a critical period of the disease in:
Ulcerative colitis
Regional enteritis
12. Nervous System :
Acute exacerbations of multiple sclerosis
13. Miscellaneous :
Tuberculous meningitis with subarachnoid block or impending block when used concurrently with appropriate antituberculous chemotherapy
Trichinosis with neurologic or myocardial involvement

Generic Hydrocortisone Tablets (Hisone) - Dosage

The initial dosage of hydrocortisone tablets may vary from 20 mg to 240 mg of hydrocortisone per day depending on the specific disease entity being treated. In situations of less severity lower doses will generally suffice while in selected patients higher initial doses may be required. The initial dosage should be maintained or adjusted until a satisfactory response is noted. If after a reasonable period of time there is a lack of satisfactory clinical response, hydrocortisone tablets should be discontinued and the patient transferred to other appropriate therapy.
Replacement therapy :
In chronic adrenocortical insufficiency, a dosage of 20 to 30mg a day is usually recommended, sometimes together with 4-6 g of sodium chloride or 50-300 micrograms of fludrocortisone daily.
Paediatric population: In congenital adrenal hyperplasia, 10-30 mg in divided doses is the normal daily requirement.
In chronic adrenocortical insufficiency, the dosage should be approximately 0.4 to 0.8mg/kg/day in two or three divided doses, adjusted to the needs of the individual child.
Use in serious trauma or illness with known adrenal insufficiency or doubtful adrenocortical reserve :
Paediatric population:
Doses are generally higher than that used for chronic adrenocortical insufficiency and should be selected as appropriate for the clinical situation. Pre-operative use :
Anaesthetists must be informed if the patient is taking corticosteroids or has previously taken corticosteroids.
When long term treatment is to be discontinued, the dose should be gradually reduced over a period of weeks or months, depending on dosage and duration of therapy
Acute emergencies :
60-80 mg every 4-6 hours for 24 hours then gradually reduce the dose over several days. The dosage regimen in adult and pediatric patients should be based on the current guidelines for each condition. Elderly:
Treatment of elderly patients, particularly if long term, should be planned bearing in mind the more serious consequences of the common side effects of corticosteroids in old age, especially osteoporosis, diabetes, hypertension, susceptibility to infection and thinning of the skin

Please consult your doctor for exact dosing instructions. Hisone tablets (Generic Hydrocortisone tablets) should be administered in the dose prescribed by the doctor and for the duration recommended by the doctor.

Storage

Store Hisone tablets (Generic Hydrocortisone Tablets) at controlled room temperature (59°F to 86°F, 15°C to 30°C). Protect from light.

Contraindications

Hisone tablets are contraindicated in patients with a hypersensitivity to Hydrocortisone or any inactive ingredient present in tablets. Hisone tablets are contraindicated in the following cases:
Contraindicated in infections including systemic infections where anti-infective therapy has not been started.
Patients vaccinated with live vaccines.
herpes simplex of the eye, except when used for short-term or emergency therapy as in acute sensitivity reactions
patients with vaccinia and varicella, except when used for short-term or emergency therapy as in acute sensitivity reactions

Warnings and Precautions

In patients on corticosteroid therapy subjected to unusual stress, increased dosage of rapidly acting corticosteroids before, during, and after the stressful situation is indicated.
Corticosteroids may mask some signs of infection, and new infections may appear during their use. Infections with any pathogen including viral, bacterial, fungal, protozoan or helminthic infections, in any location of the body, may be associated with the use of corticosteroids alone or in combination with other immunosuppressive agents that affect cellular immunity, humoral immunity, or neutrophil function.
These infections may be mild, but can be severe and at times fatal. With increasing doses of corticosteroids, the rate of occurrence of infectious complications increases.
There may be decreased resistance and inability to localize infection when corticosteroids are used.
Prolonged use of corticosteroids may produce posterior subcapsular cataracts, glaucoma with possible damage to the optic nerves, and may enhance the establishment of secondary ocular infections due to fungi or viruses.

Side Effects

Like all medicines, Hisone tablets can cause side effects, although not everybody gets them. People taking steroids to replace similar naturally occurring hormones should be less likely to get side effects than people taking steroids for other illnesses.
Fluid and Electrolyte Disturbances :
Sodium retention, Fluid retention, Congestive heart failure in susceptible patients, Potassium loss, Hypokalemic alkalosis and Hypertension
Musculoskeletal :
Muscle weakness, Steroid myopathy, Loss of muscle mass, Osteoporosis , Vertebral compression fractures, Aseptic necrosis of femoral and humeral heads, Pathologic fracture of long bones and Tendon rupture
Gastrointestinal :
Peptic ulcer with possible perforation and hemorrhage, Perforation of the small and large bowel, particularly in patients with inflammatory bowel disease, Pancreatitis, Abdominal distention and Ulcerative esophagitis
Dermatologic :
Impaired wound healing, Thin fragile skin, Petechiae and ecchymoses , Erythema , Increased sweating, May suppress reactions to skin tests, Other cutaneous reactions, such as allergic dermatitis, urticaria, angioneurotic edema
Neurologic :
Convulsions, Increased intracranial pressure with papilledema (pseudotumor cerbri) usually after treatment, Vertigo, Headache and Psychic disturbances
Endocrine :
Menstrual irregularities, Development of cushingoid state, Suppression of growth in children Secondary adrenocortical and pituitary unresponsiveness, particularly in times of stress, as in trauma, surgery, or illness Decreased carbohydrate tolerance, Manifestations of latent diabetes mellitus, Increased requirements for insulin or oral hypoglycemic agents in diabetics and Hirsutism
Ophthalmic :
Posterior subcapsular cataracts, Increased intraocular pressure, Glaucoma and Exophthalmos
Metabolic:
Negative nitrogen balance due to protein catabolism
Cardiovascular :
Myocardial rupture following recent myocardial infarction
Other :
Hypersensitivity, Thromboembolism , Weight gain , Increased appetite, Nausea and Malaise

Overdosage

Reports of acute toxicity and/or death following overdosage of glucocorticoids are rare. In the event of overdosage, no specific antidote is available, treatment is supportive and symptomatic.

Hydrocortisone Tablets During Pregnancy

Hydrocortisone has been classified by the US FDA as Pregnancy Category C. Administration of corticosteroids to pregnant animals can cause abnormalities of foetal development including cleft palate, intra-uterine growth retardation and effects on brain growth and development. There is no evidence that corticosteroids result in an increased incidence of congenital abnormalities, such as cleft palate / lip in man.
However, when administered for prolonged periods or repeatedly during pregnancy, corticosteroids may increase the risk of intra-uterine growth retardation. Hypoadrenalism may, in theory, occur in the neonate following prenatal exposure to corticosteroids but usually resolves spontaneously following birth and is rarely clinically important.
As with all drugs, corticosteroids should only be prescribed when the benefits to the mother and child outweigh the risks.
Do not use this medicine without your doctor's consent in case you are pregnant. Stop using this medication and inform your doctor immediately if you become pregnant during treatment.

Nursing Considerations

Corticosteroids are excreted in breast milk, although no data are available for hydrocortisone. Infants of mothers taking high doses of systemic corticosteroids for prolonged periods may have a degree of adrenal suppression. Mothers taking pharmacological doses of corticosteroids should be advised not to breast-feed.
Do not use this medication without telling your doctor if you are breast-feeding a baby.

Buy Generic Hydrocortisone 5 mg, 10 mg and 20 mg Tablets Online at Only $ 0.20 per Pill

You can buy Generic Hydrocortisone Tablets online from Clear Sky Pharmacy at a cheap price. Hisone 5 mg, 10 mg & 20 mg pills, manufactured by Samarth Life Sciences Private Limited, India , are supplied in a blister strip of 10 tablets. The 5 mg tablets cost only $0.20 per unit when you place an order for 360 tablets.

Disclaimer

The above information is provided to the best of our knowledge and in good faith, it is without a warrant of any kind, expressed or implied.

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