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Generic Gleevec (imalek By Sun Pharma)

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Brand Name(s) :

Generic Gleevec (Imalek by Sun Pharma)

Usage :   Cancer
Active Ingredient : Imatinib 100/400mg
Supplied Form : Tablet
Packaging : Blister with tablets
Qty Price Price per
Tablet
Saving  
100mg x 30 pcs USD 99.95 USD 3.33 -
100mg x 60 pcs USD 179.95 USD 3.00 USD 19.80
100mg x 90 pcs USD 249.95 USD 2.78 USD 49.50
Qty Price Price per
Tablet
Saving  
400mg x 30 pcs USD 269.95 USD 9.00 -
400mg x 60 pcs USD 519.95 USD 8.67 USD 19.80
400mg x 90 pcs USD 749.95 USD 8.33 USD 80.10

Generic Gleevec (Imatinib Mesylate Tablets) - Product Information

Generic Gleevec (Imatinib Mesylate tablets) is used for the treatment of newly diagnosed adult patients with Philadelphia chromosome positive chronic myeloid leukemia (CML) in chronic phase.

Imatinib Mesylate tablets are also used for the treatment of patients with Philadelphia chromosome positive chronic myeloid leukemia (CML) in blast crisis, accelerated phase, or in chronic phase after failure of interferon-alpha therapy.
Generic Gleevec is also used to treat pediatric patients with Ph+ chronic phase CML whose disease has recurred after stem cell transplant or who are resistant to interferon-alpha therapy.

Imatinib Mesylate tablets are also used to treat patients with Kit (CD117) positive unresectable and/or metastatic malignant gastrointestinal stromal tumors (GIST).

Imalek tablets are manufactured by Sun Pharmaceutical Industries Ltd. in the strengths of 100 mg and 400 mg.

Name of the Drug

We supply original Imalek tablets manufactured by Sun Pharmaceutical Industries Ltd..

Manufacturer of Imalek Tablets

Sun Pharmaceutical Industries Ltd.  
Website:www.sunpharma.com

Active Ingredient present in Imalek Tablets

The active ingredient present in Imalek tablets is Imatinib Mesylate. Each Imalek tablet contains 100 mg or 400 mg of Imatinib Mesylate.

Uses of Generic Gleevec (Imalek by Sun Pharma)

Generic Gleevec is used to treat a type of blood cancer called Philadelphia chromosome positive chronic myeloid leukemia (CML). Imalek is also used to treat certain tumors of the stomach and digestive system. It works by interfering with the growth of some cancer cells.

Imatinib Mesylate Tablets Dosage

The prescribed dosage should be administered orally, with a meal along with large glass of water. The recommended dosage of Generic Gleevec (Imatinib Mesylate tablets) is 400 mg/day for adult patients in chronic phase CML and 600 mg/day for adult patients in accelerated phase or blast crisis. The recommended Generic Gleevec dosage is 260 mg/m2/day for children with Ph+ chronic phase CML recurrent after stem cell transplant or who are resistant to interferon-alpha therapy.

The recommended dosage of Imatinib Mesylate tablets is 400 mg/day or 600 mg/day for adult patients with unresectable and/or metastatic, malignant GIST.
Doses of 400 mg or 600 mg should be administered once daily, whereas a dose of 800 mg should be administered as 400 mg twice a day.

In children, Imatinib Mesylate treatment can be given as a once-daily dose or alternatively the daily dose can be split into two - once in the morning and once in the evening. There is no experience with Generic Gleevec treatment in children under 3 years of age.

Patients with mild and moderate hepatic impairment should start treatment at a dose of 400 mg/day. Patients with severe hepatic impairment should start treatment at a dose of 300 mg/day.

How to Use Imatinib Mesylate Tablets

Take Imatinib Mesylate tablets exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Take this medicine with a large glass of water. This medicine should be taken with a meal.

To be sure this medicine is not causing harmful effects; your blood may need to be tested often. Your liver function may also need to be tested. Visit your doctor regularly.

Take the missed dose as soon as you remember, making sure you also eat a meal and drink a large glass of water. If it is almost time for your next meal, skip the missed dose and take the medicine when you eat your next meal. Do not take extra medicine to make up the missed dose.

Imatinib Contraindications

Imatinib tablets (Imalek) are contraindicated in patients with a hypersensitivity to Imatinib Mesylate or any inactive ingredient present in Imalek tablets.

Generic Gleevec Overdosage

Experience with ingestion of doses greater than 800 mg is limited. Rare cases of Generic Gleevec (Imatinib Mesylate) overdose have been reported. In the event of overdosage, the patient's condition should be observed and proper supportive treatment given.

Imatinib Mesylate Side effects

The most frequently reported Imatinib Mesylate side effects were edema, nausea, diarrhea, abdominal pain, muscle cramps, fatigue, and rash. Most side effects were of mild-to-moderate severity.

Get emergency medical help if you have any signs of an allergic reaction including hives, difficulty breathing, or swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious Generic Gleevec side effects:
• fever, sore throat, and headache with a severe blistering, peeling, and red skin rash
• nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes)
• fever, chills, body aches, flu symptoms
• black, bloody, or tarry stools
• coughing up blood or vomit that looks like coffee grounds
• pale skin, easy bruising or bleeding, unusual weakness
• feeling short of breath, even with mild exertion
• swelling, rapid weight gain
• urinating more or less than usual, or not at all
• sudden, severe headache, or pain behind the eyes

Less serious side effects of Imatinib Mesylate may include:
• mild nausea, diarrhea, upset stomach, gas
• muscle or joint pain
• mild skin rash
• headache, dizziness
• stuffy nose, cough, sore throat
• depression, sleep problems (insomnia)
• tired feeling

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
Overdose symptoms may include severe muscle cramps.

Warnings & Precautions When Using Imatinib Mesylate Tablets

Do not use Generic Gleevec if you are allergic to Imatinib Mesylate or any of its other ingredients.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medicine:
• liver disease
• underactive thyroid
• kidney disease
• congestive heart failure
• a history of stomach ulcer or bleeding
• if you take a warfarin (Coumadin®) blood thinner
• if you are receiving chemotherapy

This medicine can cause harm to an unborn baby. This medicine may cause injury and even death to the unborn baby if you take it during the second and third trimesters of pregnancy. Do not use this medicine without your doctor's consent if you are pregnant. Use an effective form of birth control. Stop using this medication and tell your doctor right away if you become pregnant during treatment. It is not known whether this medicine passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Do not give this medication to anyone younger than 18 years old without a doctor's advice. St. John's wort is an inducer of CYP3A4 activity and may increase metabolism and decrease Imatinib plasma concentrations.

Do not take this medicine on an empty stomach.

Imatinib Mesylate Tablets During Pregnancy

Imatinib Mesylate has been classified by the US FDA as Pregnancy Category D.

Imatinib Mesylate was teratogenic in rats when administered during organogenesis at doses equal to or greater than 100 mg/kg, approximately equal to the maximum clinical dose of 800 mg/day based on body surface area. Teratogenic effects included exencephaly or encephalocele, absent/reduced frontal and absence of parietal bones.

Female rats administered doses equal to 45 mg/kg (approximately one-half the maximum human dose of 800 mg/day based on body surface area) also experienced significant post-implantation loss as shown by either early fetal resorption or stillbirths, nonviable pups and early pup mortality between postpartum Days 0 and 4. At doses higher than 100 mg/kg, total fetal loss was noted in all animals. Fetal loss was not observed at doses equal to 30 mg/kg (one-third the maximum human dose of 800 mg).

Do not use this medicine without your doctor's consent in case you are pregnant. Stop using this medication and inform your doctor immediately if you become pregnant during treatment.

Nursing Considerations

It is not known at present whether imatinib mesylate or its metabolites are excreted in human milk.

However, in lactating female rats administered 100 mg/kg, a dose approximately equal to the maximum clinical dose of 800 mg/day based on body surface area, Imatinib and its metabolites were extensively excreted in milk. Concentration in milk was approximately three-fold higher than in plasma.

Do not use this medication without telling your doctor if you are breast-feeding a baby.

Buy Imatinib Mesylate Pills Online at Only $2.78 per Pill

You can buy Generic Gleevec tablets online from Clear Sky Pharmacy at a cheap price. Imatinib Mesylate (Imalek) 100 mg and 400 mg pills, manufactured by Sun Pharmaceutical Industries Ltd., India are supplied in a blister strip of 10 tablets. The 100 mg tablets cost only $2.78 per unit when you place an order for 90 tablets.

Disclaimer

The above information is provided to the best of our knowledge and in good faith, it is without a warrant of any kind, expressed or implied.

 

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