Selgin (Selegiline HCl Tablets) - Product Information
Selgin (Selegiline HCl Tablets) a monoamine oxidase type B (MAO-B) inhibitor, is used as an additional medication in the management of patients with Parkinson's disease being treated with Levodopa/Carbidopa who show deterioration in the quality of their response to this therapy.
Beneficial effects were also seen in measures of reduced end of dose akinesia, decreased tremor and sialorrhea, improved speech and dressing ability and improved overall disability as assessed by walking and comparison to previous condition.
Selgin tablets (Generic Eldepryl) are manufactured by Intas Pharmaceuticals Ltd. in the strengths of 5 mg of Selegiline HCl.
Name of the Drug
We supply original Selgin tablets manufactured by Intas Pharmaceuticals Ltd..
Manufacturer of Selgin Tablets
Intas Pharmaceuticals Ltd.
Active Ingredient present in Selgin Tablets
The active ingredient present in Selgin tablets is Selegiline HCl. Each tablet of Selgin contains 5 mg of Selegiline HCl.
Uses of Selgin (Selegiline HCl Tablets)
Generic Eldepryl (Selgin 5 mg tablets) prevents the breakdown of a chemical in your brain called Dopamine. Low levels of Dopamine are associated with Parkinson's disease.
Selegiline HCl tablets (Selgin 5 mg by Intas Pharmaceuticals Ltd.) is used to help control the symptoms of Parkinson's disease.
Start Selegiline treatment with 1.25 mg given once a day for at least 6 weeks; after 6 weeks, the dose may be escalated to 2.5 mg once a day. Place the tablet on top of the tongue where the tablet will disintegrate in a few seconds. Avoid food and liquid intake 5 minutes before and after each dose.
In patients with mild or moderate hepatic impairment, the dose should be reduced to 1.25 mg. Selgin tablets are not recommended in patients with severe hepatic impairment.
Selegiline Tablets and Bodybuilding
Selegiline hydrochloride is a medicine used for the treatment of early-stage Parkinson’s disease and senile dementia. Bodybuilders find it useful during useful Post Cycle Therapy (PCT) because it’s an anti-depressant and also helps in the general well-being of the bodybuilders.
For strength/speed athletes, it can be even more beneficial. Since Selegiline can really boost the learning ability when it comes to learning new skills, improve reaction time, and help athletes be more efficient.
Selgin (Selegiline HCl Tablets) Contraindications
Selgin tablets (Generic Eldepryl) are contraindicated in in patients with a known hypersensitivity to Selegiline hydrochloride or any inactive ingredient present in Selgin tablets.
Selgin tablets are also contraindicated for use with Meperidine and other opioids.
Selegiline Side Effects
The most commonly occurring Selegiline side effects with incidence at least 3% greater than on placebo are constipation, skin disorders, vomiting, dizziness, dyskinesia, insomnia, dyspnea, myalgia, and rash.
In pre-marketing studies, the following side effects caused, in decreasing order of frequency, to stopping of treatment with Selegiline: nausea, hallucinations, confusion, depression, loss of balance, insomnia, orthostatic hypotension, increased akinetic involuntary movements, agitation, arrhythmia, bradykinesia, chorea, delusions, hypertension, new or increased angina pectoris, and syncope.
Adverse effects reported only once as a cause of discontinuation are ankle edema, anxiety, burning lips/mouth, constipation, drowsiness/lethargy, dystonia, excess perspiration, increased freezing, gastrointestinal bleeding, hair loss, increased tremor, nervousness, weakness, and weight loss.
Some patients exposed to doses of 600 mg of d,l-Selegiline suffered severe hypotension and psychomotor agitation.
Signs and symptoms of Selegiline overdosage can include, alone or in combination, any of the following symptoms: drowsiness, dizziness, faintness, irritability, hyperactivity, agitation, severe headache, hallucinations, trismus, opisthotonos, convulsions, and coma; rapid and irregular pulse, hypertension, hypotension and vascular collapse; precordial pain, respiratory depression and failure, hyperpyrexia, diaphoresis, and cool, clammy skin.
Treatment of Selegiline overdose with non-selective MAOIs is symptomatic and supportive. Induction of emesis or gastric lavage with instillation of charcoal slurry can be helpful in early poisoning, provided the airway has been protected against aspiration.
Signs and symptoms of central nervous system stimulation, including convulsions, should be treated with diazepam, given slowly intravenously. Phenothiazine derivatives as well as central nervous system stimulants must be avoided. Hypotension and vascular collapse must be treated with intravenous fluids and, if required, blood pressure titration with an intravenous infusion of a dilute pressor agent.
Warnings And Precautions
Below are the warnings and precautions when undergoing treatment with Selegiline tablets.
- May cause hypertension above 2.5 mg/day
- May cause serotonin syndrome when used with antidepressants
- May cause falling asleep during activities of daily living
- May cause hypotension/orthostatic hypotension
- May cause or exacerbate dyskinesia
- May cause hallucinations and psychotic-like behavior
- May cause problems with impulse control and compulsive behaviors
- Abrupt discontinuation may cause hyperpyrexia and confusion
- Increased risk of melanoma
- May cause irritation of the buccal mucosa
- Increased risk for phenylketonuric patients
Selegiline During Pregnancy
Selegiline has been classified by the US FDA as Pregnancy Category C.
No teratogenic effects were observed in a study of embryo-fetal development in rats at oral doses of 4, 12 and 35 times the human therapeutic dose on a mg/m2 basis. In the rat study, there was a decrease in fetal body weight at the highest dose tested. There are no adequate and well-controlled studies conducted in pregnant women. Selegiline should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Do not use this medicine without your doctor's consent in case you are pregnant. Stop using this medication and inform your doctor immediately if you become pregnant during treatment.
It is not known whether Selegiline HCl is excreted in human milk. Because many drugs are excreted in human milk, consideration should be given to discontinuing the use of all but absolutely essential medicines in treating in nursing women.
Do not use this medication without telling your doctor if you are breast-feeding a baby.
Buy Generic Eldepryl Online at Only $0.30 per Pill
You can buy Generic Eldepryl online from Clear Sky Pharmacy at a cheap price. Selgin 5 mg pills, manufactured by Intas Pharmaceuticals Ltd., India are supplied in a blister strip of 10 tablets. The 5 mg tablets cost only $0.30 per unit when you place an order for 300 tablets.
The above information is provided to the best of our knowledge and in good faith, it is without a warrant of any kind, expressed or implied.
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